Related Experiment Video
Updated: Jul 18, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma
Published on: July 17, 2013
Poorly differentiated squamous cell carcinoma coexisting with angiofibroma and spreading as intravascular emboli in
Kajal Dhingra1, Niti Singhal, Nita Khurana
1Department of Pathology, Maulana Azad Medical College, New Delhi, India.
Abstract:
We report a case of a 28-year-old male who presented with epistaxis and hyponasal speech. A clinical and radiological diagnosis of nasopharyngeal angiofibroma was made. The patient underwent a modified transpalatal resection of the tumor under general anesthesia. A diagnosis of poorly differentiated carcinoma, possibly squamous, with extensive embolization in the vessels of angiofibroma was made. As the two entities have entirely different management and outcome, it is imperative to distinguish and locate the malignant component.
Related Concept Videos
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
The Tumor Microenvironment
Tumor Progression
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Cancer Cell Migration through Invadopodia
