Related Experiment Video
Updated: Jul 18, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
Published on: August 15, 2025
What happens now? Ongoing outcome after post-temporal lobectomy seizure recurrence
Anne M McIntosh1, Samuel F Berkovic
1Epilepsy Research Centre, School of Nursing, Department of Medicine, University of Melbourne, Victoria, Australia. a.mcintosh@unimelb.edu.au
Abstract:
We studied outcome subsequent to the initial post-temporal lobectomy seizure recurrence (n = 202) or remission. Two years after recurrence, there was 74% (95% CI 67% to 79%) probability of further seizures. Two years after a 2-year seizure remission, there was 68% (95% CI 52% to 79%) probability of remaining seizure-free (n = 50). Remission after seizures had a significantly poorer outcome than an equivalent period of complete seizure freedom after surgery. Implications for outcome classification are discussed.
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