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Recombinant tissue plasminogen activator (r-TPA) in fibrin dissolution due to postoperative endophthalmitis
Yasmin Riaz1, Jodhbir S Mehta, Arosho Fernando
1The Western Eye Hospital, Marylebone Road, London, UK.
Introduction:
The aim of this paper was to describe the use of r-TPA for fibrin clot dissolution following endophthalmitis.
Clinical Picture:
A 74-year-old man presented with painful loss of vision following routine uncomplicated cataract surgery.
Treatment:
He underwent standard treatment for postoperative endophthalmitis but despite this, developed a dense fibrin clot. He underwent further intracameral injection of r-TPA.
Outcome:
Following the injection, he had complete clot dissolution within 2 hours without any complications.
Conclusion:
R-TPA may be used effectively in the treatment of fibrin clots secondary to endophthalmitis following cataract surgery.
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