Related Experiment Video
Updated: Jul 10, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
Published on: January 8, 2015
Nor-seco-cucurbit[10]uril exhibits homotropic allosterism
Wei-Hao Huang1, Simin Liu, Peter Y Zavalij
1Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Abstract:
The condensation of glycoluril and formaldehyde in concentrated HCl at 50 degrees C delivers nor-seco-cucurbit[10]uril (ns-CB [10]). 1H NMR and X-ray crystallographic evidence indicates that the two cavities of ns-CB[10] accommodate guests that are typically bound within CB[6] or CB[7]. Several interesting types of selectivity are possible within these ternary complexes-top/center isomerism, diastereoselective complexation of chiral (but racemic) guest pairs, and guest size controlled homotropic allosterism.
Related Concept Videos
Mate Choice
Self-Discrepancy Theory
Test for Homogeneity
Multiple Comparison Tests
It would be easy to compare two samples using a significance alpha level of 0.05. In other words, there is only one sample pair to be compared. However, it would be difficult to identify a significantly different sample if the number...
The Bell Curve
This pattern applies to many human characteristics beyond intelligence, such as height. For example, if you...
Causes of Similarity-Dissimilarity Effect

