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Allergic contact dermatitis from eosin
1Clinique Dermatologique, Hôpital Civil, Strasbourg, France.
Contact Dermatitis
|January 1, 1991
Summary
Eosin sensitivity, once common, reappeared in 4 patients due to topical bacteriostatic preparations. Patch tests confirmed eosin allergy, likely caused by an impurity, not eosin itself.
Area of Science:
- Dermatology
- Allergology
- Toxicology
Background:
- Historically, eosin sensitivity and lipstick cheilitis were prevalent before 1960.
- Eosin, a dye, was a common ingredient in cosmetics and topical preparations.
Observation:
- Four patients presenting in 1988-1989 exhibited symptoms suggestive of eosin sensitivity.
- These patients had used topical bacteriostatic preparations prior to symptom onset.
Findings:
- All four patients demonstrated positive patch tests to eosin.
- The clinical presentation and patch test results suggest sensitization to an impurity within the eosin used in topical preparations, rather than eosin itself.
Implications:
- Re-emergence of eosin sensitivity highlights the importance of product purity in topical formulations.
- Identifying impurities as allergens is crucial for preventing adverse reactions and improving cosmetic and dermatological safety.