Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Cardiac Output01:17

Exercise and Cardiac Output

Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be met...
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
Hypoxia01:23

Hypoxia

Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
Factors Affecting Respiration01:24

Factors Affecting Respiration

Respiration is a crucial physiological function involving exchanging oxygen (O2) and carbon dioxide (CO2) between an organism and its environment. Various factors can impact this essential process:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sarcomas developed in patients with Lynch Syndrome are enriched in pleomorphic soft-tissue sarcomas and are sensitive to immunotherapy.

European journal of cancer (Oxford, England : 1990)·2025
Same author

The multifaceted aspects of sleep and sleep-wake disorders following stroke.

Revue neurologique·2023
Same author

[CAR-T cells therapy in solid tumors : where are we now ?]

Revue medicale de Liege·2022
Same author

[Apalutamide, Erleada®].

Revue medicale de Liege·2022
Same author

Impact of drug consumption rooms on non-fatal overdoses, abscesses and emergency department visits in people who inject drugs in France: results from the COSINUS cohort.

International journal of epidemiology·2022
Same author

[Management of metastatic hormone-naive prostate cancer at diagnosis].

Revue medicale de Liege·2021

Related Experiment Video

Updated: Jul 18, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
10:00

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

Evidence of decrease in peak heart rate in acute hypoxia: effect of exercise-induced arterial hypoxemia.

O Grataloup1, T Busso, J Castells

  • 1Unité de recherche Physiologie et Physiopathologie de l'Exercice et Handicap, Université J. Monnet, Saint-Etienne, France. olivier.grataloup@gmail.com

International Journal of Sports Medicine
|November 18, 2006
PubMed
Summary

Endurance athletes experiencing exercise-induced arterial hypoxemia show a greater reduction in peak heart rate during acute hypoxia. Arterial oxygen saturation significantly influences this heart rate decrease in cyclists.

More Related Videos

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

Related Experiment Videos

Last Updated: Jul 18, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
10:00

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise
09:33

Using Near-Infrared Spectroscopy Wearable Devices to Identify Central Versus Peripheral Limitations During Exercise

Published on: December 19, 2024

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

Area of Science:

  • Exercise Physiology
  • Cardiovascular Response
  • Hypoxia Research

Background:

  • Acute moderate hypoxia can affect physiological responses during exercise.
  • Exercise-induced arterial hypoxemia (EIAH) is observed in some endurance athletes.
  • Understanding the relationship between oxygen saturation and heart rate is crucial for performance.

Purpose of the Study:

  • To investigate the influence of arterial oxygen saturation at exhaustion on peak heart rate.
  • To compare responses between cyclists with and without exercise-induced arterial hypoxemia.
  • To determine the impact of acute hypoxia on heart rate and oxygen uptake.

Main Methods:

  • Nineteen male cyclists performed exhaustive ramp exercise under normoxia and normobaric hypoxia.
  • Subjects were categorized based on the presence of exercise-induced arterial hypoxemia (>5% SaO2 decrease).
  • Measurements included oxygen uptake, heart rate, and arterial oxygen saturation (SaO2).

Main Results:

  • Peak heart rate decreased under hypoxia in both groups, with a greater reduction in hypoxemic subjects.
  • Arterial oxygen saturation was lower in hypoxemic subjects during hypoxia.
  • A correlation was found between reduced SaO2 and the fall in peak heart rate.

Conclusions:

  • Hypoxemic cyclists exhibit a more pronounced decrease in peak heart rate during acute hypoxia.
  • Arterial oxygenation level at exhaustion significantly influences peak heart rate reduction in hypoxia.
  • These findings highlight the impact of EIAH on cardiovascular response to hypoxic exercise.