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Preoperative helical computerized tomography estimation of donor liver volume
1Ege Universitesi Tip Fakultesi, Genel Cerrahi Anabilim Dali Bornova, Izmir, Turkey.
Transplantation Proceedings
|November 23, 2006
Summary
Helical computed tomography (CT) accurately measures total and segmental liver volumes in living donors. This imaging is crucial for selecting donors and surgical approaches, preventing complications like hepatic failure.
Area of Science:
- Radiology
- Hepatology
- Surgical Oncology
Background:
- Accurate liver volume assessment is vital for living donor transplantation.
- Potential donors require precise measurements to ensure safety and graft suitability.
- Computed tomography (CT) is a key imaging modality in this evaluation.
Purpose of the Study:
- To evaluate the accuracy of spiral CT and 3-D imaging in measuring liver volumes for living donors.
- To compare CT-based volume estimates with intraoperative measurements.
- To determine the clinical utility of CT in donor selection and surgical planning.
Main Methods:
- A prospective study involving 150 potential living liver donors.
- Helical CT scans were used to estimate total and segmental liver volumes preoperatively.
- Correlation analysis was performed between CT estimates and intraoperative graft weight measurements.
Main Results:
- A significant correlation (P < .05) was found between preoperative CT volume estimates and intraoperative graft weight.
- CT volume measurements explained 97.7% of the variance in graft mass (R2: 0.977).
- Helical CT demonstrated high accuracy in determining liver volumes.
Conclusions:
- Preoperative CT estimation of liver volumes is essential for avoiding donor-recipient size mismatch.
- Accurate volume assessment impacts donor selection and surgical strategy, preventing post-harvest hepatic failure.
- Helical CT is a reliable tool for assessing total and segmental liver volumes in potential living donors.

