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Published on: June 18, 2021
Brain abscess following intracerebral haemorrhage
K Nakai1, T Yamamoto, S Yasuda
1Department of Neurosurgery, Institute of Clinical Medicine, Graduate School of Comprehensive Human Sciences, Major of Functional and Regulatory Medical Sciences, University of Tsukuba, Tennodai 1-1-1, Tsukuba, Ibaraki, 305-8575 Japan.
Abstract:
We report two cases of brain abscess, which developed at the site of an intracerebral haemorrhage (ICH) in a 75-year-old man and a 32-year-old-man. The patients recovered after surgical treatment and systemic antibiotic therapy. The route of infection could not be detected in either case. The literature contains only 13 reported cases of brain abscess as a complication of ICH. Although the interval from initial ICH to abscess formation ranged from 4 to 20 weeks, almost all patients had episodes of high fever, indicating the presence of systemic infection and bacterial seeding, 0-14 days after the onset of their ICH. Therefore, abscess formation appears to be caused by haematogenous seeding of infection in patients with ICH. Abscess formation should be considered when a patient deteriorates clinically with a febrile episode after an ICH.
Insights
Brain abscesses can develop after intracerebral hemorrhage (ICH). Prompt recognition and treatment of fever following ICH are crucial for managing this rare complication.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- Intracerebral hemorrhage (ICH) is a serious neurological condition.
- Brain abscesses are rare but severe complications following ICH.
Observation:
- Two cases of brain abscess developing at the site of ICH are presented.
- Patients were treated successfully with surgery and antibiotics.
Findings:
- Abscess formation occurred 4-20 weeks after ICH.
- Most patients experienced fever shortly after ICH, suggesting hematogenous seeding.
- The exact route of infection remains undetermined in these cases.
Implications:
- Consider brain abscess in patients with ICH who develop fever and clinical deterioration.
- Early diagnosis and intervention are critical for favorable outcomes in ICH-associated brain abscess.
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