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Interfacial Molecular-level Structures of Polymers and Biomacromolecules Revealed via Sum Frequency Generation Vibrational Spectroscopy
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Sum-frequency generation spectroscopy of DNA monolayers

Yannick Sartenaer1, Gérard Tourillon, Laurent Dreesen

  • 1Laboratoire de Spectroscopie Moléculaire de Surface, Université de Namur, 61 rue de Bruxelles, B-5000 Namur, Belgium. yannick.sartenaer@fundp.ac.be

Biosensors & Bioelectronics
|November 23, 2006
PubMed
Summary

Thiolated single-stranded DNA (HS-ssDNA) on platinum shows buffer molecules intercalated within the monolayer. Rinsing or using specific buffer salts minimizes this interference for better analysis of DNA self-assembly.

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