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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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Related Experiment Video

Updated: Jul 18, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
10:31

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Transplantation osteoporosis.

Carolina A M Kulak1, Victoria Z C Borba, Jaime Kulak Júnior

  • 1SEMPR, Department of Endocrinology and Metabology, Federal University of Parana, PR, Brazil.

Arquivos Brasileiros De Endocrinologia E Metabologia
|November 23, 2006
PubMed
Summary

Organ transplantation improves survival but can lead to osteoporosis and fractures. This review covers bone loss mechanisms and management strategies before and after various organ transplants.

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Transplantation Into the Mouse Ovarian Fat Pad
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Transplantation Into the Mouse Ovarian Fat Pad

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Last Updated: Jul 18, 2026

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
10:31

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Transplantation Into the Mouse Ovarian Fat Pad
09:25

Transplantation Into the Mouse Ovarian Fat Pad

Published on: September 7, 2016

Area of Science:

  • Transplantation Medicine
  • Endocrinology
  • Bone Metabolism

Background:

  • Organ transplantation has increased globally, improving patient survival and quality of life.
  • Osteoporosis and fragility fractures are significant complications following organ transplantation.
  • Pre-existing bone disease is common in end-stage organ failure patients.

Purpose of the Study:

  • To review the mechanisms of bone loss in the early and late post-transplant periods.
  • To discuss bone loss specific to kidney, lung, liver, cardiac, and bone marrow transplantation.
  • To outline prevention and treatment strategies for post-transplant osteoporosis.

Main Methods:

  • Literature review of mechanisms of bone loss post-transplantation.
  • Analysis of specific bone loss features after different types of organ transplants.
  • Synthesis of current knowledge on osteoporosis management in transplant recipients.

Main Results:

  • Bone loss occurs in both early and late post-transplant phases due to multiple factors.
  • Specific patterns of bone disease are observed after different organ transplantations.
  • Effective management requires intervention before and after transplantation.

Conclusions:

  • Post-transplant osteoporosis is a complex issue requiring a multi-faceted approach.
  • Early and continuous management is crucial for preventing fractures.
  • Further research is needed to optimize bone health in transplant recipients.