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Benign splenic epithelial cyst accompanied by elevated Ca 19-9 level: a case report.
Rafet Yigitbasi1, Ilhan Karabicak, Fatih Aydogan
1Department of General Surgery, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.
The Mount Sinai Journal of Medicine, New York
|November 23, 2006
Summary
A rare benign epidermoid splenic cyst caused elevated cancer antigen 19-9 (CA 19-9) levels in a 30-year-old woman. Surgical removal of the splenic cyst normalized the CA 19-9 serum level, confirming the cyst as the source.
Area of Science:
- Gastroenterology and Hepatology
- Surgical Oncology
Background:
- True non-parasitic splenic cysts are exceptionally rare, with fewer than 30 documented cases.
- Elevated cancer antigen 19-9 (CA 19-9) levels can indicate various conditions, including malignancies and benign pathologies.
Observation:
- A 30-year-old female presented with a benign epidermoid splenic cyst and significantly elevated serum CA 19-9 levels (268 U/mL).
- The patient underwent surgical resection of the splenic cyst and splenectomy.
Findings:
- Post-surgical normalization of serum CA 19-9 levels within six weeks confirmed the cyst as the source of the elevation.
- This case highlights a rare instance of a benign splenic cyst mimicking a malignancy marker.
Implications:
- Accurate diagnosis and management of rare splenic pathologies are crucial to avoid misdiagnosis of cancer.
- Further research into the mechanisms linking benign splenic cysts to elevated tumor markers like CA 19-9 is warranted.
