Related Experiment Video
Updated: Jul 18, 2026

Optogenetic Manipulation of Neural Circuits During Monitoring Sleep/wakefulness States in Mice
Published on: June 19, 2019
Sleep and psychiatric disorders: future directions
1Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710, USA. kryst001@mc.duke.edu
Abstract:
Understanding of the relationship between co-occurring sleep and psychiatric disorders has undergone a radical change. The longstanding perspective that sleep problems invariably are a symptom of a psychiatric disorder is giving way to understanding that complex bidirectional relationships may exist. This change has opened doors to new directions in research and led to changes in guidelines for clinical practice. This article discusses promising future directions for building on this foundation, including developing lines of research currently underway, studying mechanisms that underlie the relationships between sleep and psychiatric disorders; and developing treatment strategies that target these mechanisms to lead to better treatment of sleep disorders and psychiatric disorders.
Related Concept Videos
Sedatives and Hypnotics Drugs: Miscellaneous Agents
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Understanding Sleep
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Nightmares and Night Terrors
Nightmares often...
Management of Insomnia
Narcolepsy

