Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gamma testing experience with the ACL TOP hemostasis testing system.

Daniel K H Ho1, Marni Lollo, Marian Reyes

  • 1Hematology Division, Department of Laboratory Medicine, St. Michael's Hospital, Toronto, Ontario, Canada. hod@smh.toronto.on.ca

Laboratory Hematology : Official Publication of the International Society for Laboratory Hematology
|November 23, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of clopidogrel hypersensitivity reactions and management with oral steroids without clopidogrel discontinuation.

Journal of the American College of Cardiology·2011
Same author

Recent progress in understanding the pathogenesis of immune thrombocytopenia.

Current opinion in hematology·2010
Same author

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell-mediated responses that are differentially sensitive to therapy.

Blood·2009
Same author

A patient with anemia of obscure origin: Crohn's disease in disguise.

Nature clinical practice. Gastroenterology & hepatology·2006
Same author

Experience of implementing a quality management system in an Ontario hospital laboratory.

Clinical leadership & management review : the journal of CLMA·2005
Same author

Immunoadsorption of factor VIII inhibitors.

Current opinion in hematology·2005
Same journal

Erythrocyte phosphatidylserine exposure in β-thalassemia.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2014
Same journal

Antineutrophil cytoplasmic antibody-associated neutropenia in a patient with type 1 diabetes mellitus.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2014
Same journal

Rapid separation of mononuclear hodgkin from multinuclear reed-sternberg cells.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2014
Same journal

Induction of fetal hemoglobin as a novel therapeutic strategy for β-hemoglobinopathy.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2014
Same journal

Characteristic scattergram of white blood cells obtained using the Pentra MS CRP hematology analyzer in a patient with neutral lipid storage disease.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2013
Same journal

Pathogenetic role of Factor VII deficiency and thrombosis in cross-reactive material positive patients.

Laboratory hematology : official publication of the International Society for Laboratory Hematology·2013
See all related articles

The ACL TOP coagulation analyzer is precise and suitable for high-volume labs. It offers double the throughput for thrombophilia workups compared to the ACL ADVANCE, meeting demanding turnaround times.

Area of Science:

  • Clinical laboratory science
  • Hematology
  • Coagulation diagnostics

Background:

  • High-volume specialized coagulation laboratories require precise and efficient hemostasis testing platforms.
  • Evaluating new instrumentation is crucial for optimizing laboratory workflow and turnaround times.

Purpose of the Study:

  • To assess the performance of the ACL TOP coagulation analyzer in a high-volume laboratory setting.
  • To determine the precision, normal ranges, and reagent sensitivities of the ACL TOP.
  • To compare the analytical correlation and throughput of the ACL TOP with the ACL ADVANCE.

Main Methods:

  • Gamma testing of the ACL TOP analyzer.
  • Determination of instrument precision, normal ranges, and factor sensitivities.
  • Analytical correlation studies against the ACL ADVANCE analyzer.

Related Experiment Videos

  • Throughput evaluation for routine and specialized hemostasis assays, including thrombophilia workups.

    • Main Results:

    • The ACL TOP demonstrated acceptable instrument precision, normal reference range assignment, and factor sensitivities.
    • Favorable analytical correlation was observed between the ACL TOP and the ACL ADVANCE.
    • The ACL TOP exhibited twice the throughput for thrombophilia workups compared to the ACL ADVANCE.
    • The instrument achieved a rapid reporting rate of nearly 5 results per minute.

    Conclusions:

    • The ACL TOP is a precise coagulation analyzer suitable for high-volume, specialized hemostasis laboratories.
    • Its high throughput and speed meet the demands of fast-paced clinical settings with critical turnaround times.
    • The ACL TOP demonstrates suitability for both routine and specialized coagulation testing.