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Cochlear pharmacokinetics with local inner ear drug delivery using a three-dimensional finite-element computer model

Stefan K Plontke1, Norbert Siedow, Raimund Wegener

  • 1Department of Otorhinolaryngology, Head and Neck Surgery, Tübingen Hearing Research Center (THRC), University of Tübingen, Tübingen, Germany. stefan.plontke@uni-tuebingen.de

Audiology & Neuro-Otology
|November 23, 2006
PubMed
Summary

Three-dimensional (3D) finite-element simulations accurately model drug dispersal in cochlear fluids. This approach is crucial for optimizing local drug delivery for inner ear disorders, improving treatment safety and efficacy.

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