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Related Concept Videos

Tracheostomy Care II: Procedure01:25

Tracheostomy Care II: Procedure

Tracheostomy care is an essential nursing skill that involves cleaning and maintaining a tracheostomy tube to prevent infection and other complications. Here's a step-by-step guide explaining each procedure with its rationale. Note that disposable gloves are to be worn at all times and changed as often as needed to maintain a sterile work environment, and to protect both patient and healthcare worker.
Step 1: Perform hand hygiene, and put on personal protective equipment: gown, gloves, mask and...
Ostomy Care01:24

Ostomy Care

Introduction
An ostomy is a surgical procedure that creates an artificial opening from the intestines to the outside of the body, allowing for the rerouting of effluent. This opening is known as a stoma. A stoma usually protrudes above the skin surface, appearing pink or red, moist, and round, and it lacks nerve sensations.
There are different types of ostomies, including colostomies, ileostomies, and urostomies:
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned under...
PPE Use in Healthcare Settings II: Doffing01:10

PPE Use in Healthcare Settings II: Doffing

The sequence of removing or doffing PPE starts with the gloves, as they are the most contaminated. Next is removal of the face shield or goggles, as they would interfere with removing other PPE. Then remove the gown, followed by the mask or respirator. Perform hand hygiene between steps if hands become contaminated and immediately after removing all PPE. Generally, the outside front and sleeves of the isolation gown, the goggles or the mask, the respirator, and the face shield are contaminated.
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
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Barriers to Effective Communication II01:21

Barriers to Effective Communication II

The barriers to effective communication also include cultural barriers, semantic barriers, gender barriers, and time constraints.
Cultural barriers:
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Semantic barriers:
As a result of their tendency to use...

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Related Experiment Video

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A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage
03:42

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage

Published on: February 17, 2026

Facilitating facial retinization through barrier improvement.

Zoe Diana Draelos1, Keith D Ertel, Cynthia A Berge

  • 1Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA. zdraelos@northstate.net

Cutis
|November 24, 2006
PubMed
Summary

Preconditioning skin with a barrier-enhancing moisturizer before and during topical tretinoin therapy can reduce irritation and improve treatment outcomes for photodamaged skin.

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Area of Science:

  • Dermatology
  • Cosmetic Science
  • Skin Barrier Research

Background:

  • Topical tretinoin is used for photodamaged skin but causes irritation due to stratum corneum barrier compromise.
  • Early-phase retinization side effects limit tretinoin's utility.

Purpose of the Study:

  • To investigate if a barrier-enhancing cosmetic moisturizer can mitigate tretinoin-induced irritation.
  • To determine if preconditioning and continued use of such a moisturizer improves retinization outcomes.

Main Methods:

  • A paired, double-blinded study involving women with facial photodamage.
  • Application of two different moisturizers (one vitamin-enriched, one without) to opposite sides of the face for 10 weeks.
  • Commencement of 0.025% tretinoin cream treatment after 2 weeks, with ongoing moisturizer use.

Main Results:

  • The vitamin-enriched moisturizer enhanced stratum corneum barrier function.
  • Preconditioning and continued use of the barrier-enhancing moisturizer facilitated early retinization.
  • The barrier-enhancing moisturizer augmented the overall treatment response to tretinoin.

Conclusions:

  • Improving stratum corneum barrier function with a cosmetic moisturizer is key to mitigating tretinoin-induced irritation.
  • Barrier enhancement facilitates the early phase of facial retinization.
  • The use of barrier-enhancing moisturizers can augment tretinoin treatment efficacy for photodamaged skin.