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Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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Related Experiment Video

Updated: Jul 18, 2026

Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood

Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood

Published on: September 14, 2017

Stem cells from umbilical cord blood.

Juan Sanchez-Ramos¹

¹Department of Neurology, University of South Florida, Tampa, Florida 33612, USA. jsramos@hsc.usf.edu

Seminars in Reproductive Medicine

|November 24, 2006

Summary

Cord blood stem cells offer potential beyond bone marrow reconstitution. This review explores their plasticity and therapeutic applications for nervous system repair.

Area of Science:

Stem Cell Biology
Hematopoiesis
Neuroscience

Background:

Hematopoiesis, the lifelong generation of blood cell lines, offers valuable models for stem cell biology.
Bone marrow and cord blood transplantation are established therapies for blood diseases.
Recent research expands stem cell biology to embryonic, fetal, and adult tissues, revealing new perspectives on tissue-specific stem cells.

Purpose of the Study:

To review the biology of cord blood stem cells.
To explore their plasticity.
To discuss their therapeutic potential for nervous system repair.

Main Methods:

Literature review of stem cell biology research.
Analysis of cord blood stem cell characteristics.

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Generation of Mesenchymal Stem Cells from Human Umbilical Cord Tissue and their Differentiation into the Skeletal Muscle Lineage

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Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood

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Evaluation of potential applications in neural repair.

Main Results:

Cord blood stem cells possess plasticity beyond their hematopoietic role.
Their biological properties suggest potential for nervous system repair.
This contrasts with traditional uses in bone marrow reconstitution.

Conclusions:

Cord blood stem cells represent a promising source for regenerative medicine.
Their plasticity warrants further investigation for neurological applications.
Future research should focus on harnessing these cells for nervous system repair.