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Childhood Asthma Management Program: lessons learned.

Robert C Strunk1,

  • 1Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine and St Louis Children's Hospital, St Louis, MO 63110, USA. strunk@kids.wustl.edu

The Journal of Allergy and Clinical Immunology
|November 28, 2006
PubMed
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Long-term inhaled corticosteroid therapy improved asthma symptoms and airway responsiveness in children. However, it did not show a continued effect on lung growth during extended follow-up.

Area of Science:

  • Pediatric Pulmonology
  • Clinical Asthma Research
  • Long-term Intervention Studies

Background:

  • The National Heart, Lung, and Blood Institute Childhood Asthma Management Program (CAMP) is a landmark study.
  • It is the largest and most comprehensive investigation of long-term anti-inflammatory therapy for mild to moderate childhood asthma.
  • The study enrolled over 1000 children with persistent asthma.

Purpose of the Study:

  • To review key findings from the CAMP study.
  • To share lessons learned from conducting a decade-long research project in pediatric asthma.
  • To evaluate the long-term impact of anti-inflammatory treatment on children's asthma management.

Main Methods:

  • Longitudinal study design.
  • Inclusion of over 1000 children with persistent asthma.

Related Experiment Videos

  • Focus on anti-inflammatory interventions, specifically inhaled corticosteroids.

    • Main Results:

    • Long-term inhaled corticosteroid (ICS) treatment demonstrated sustained improvement in asthma symptoms.
    • Airway responsiveness remained improved with continued ICS use.
    • A key finding was the absence of a continued effect of ICS on lung growth during the long-term follow-up period.

    Conclusions:

    • While inhaled corticosteroids effectively manage asthma symptoms and airway responsiveness in children long-term, their impact on lung growth may not be sustained.
    • The CAMP study provides valuable insights into the complexities of managing childhood asthma over extended periods.
    • Further research is needed to understand the long-term effects of asthma interventions on lung development.