Introduction to photodynamic therapy: early experience

Photodynamic therapy (PDT) has become one of the newest and most exciting therapies being used by dermatologic surgeons from all around the world. The earliest uses of PDT can be traced to the early 1900s. This article traces the history of PDT through the discovery of the first topical photosensitizer by Kennedy and his colleagues in 1990 to its uses today in everyday dermatology practices. The two commercially available photosensitizers are reviewed and their primary uses are summarized. PDT is a useful modality that is finding new and exciting niches in today's dermatologic world.