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The mouse Gene Expression Database (GXD): 2007 update.

Constance M Smith1, Jacqueline H Finger, Terry F Hayamizu

  • 1The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

Nucleic Acids Research
|November 30, 2006
PubMed
Summary
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The Gene Expression Database (GXD) offers comprehensive mouse gene expression data, focusing on development. It integrates diverse data types and links to other Mouse Genome Informatics (MGI) resources for deeper biological insights.

Area of Science:

  • Developmental Biology
  • Genomics
  • Bioinformatics

Background:

  • The Gene Expression Database (GXD) is a key resource for mouse gene expression data.
  • Understanding gene expression patterns is crucial for studying developmental processes and diseases.

Purpose of the Study:

  • To provide an extensive and searchable database of mouse gene expression information.
  • To integrate various data types for comprehensive gene expression pattern analysis.
  • To facilitate insights into molecular biology underlying development and disease.

Main Methods:

  • Integration of diverse gene expression data (transcripts, proteins).
  • Linking GXD data with other Mouse Genome Informatics (MGI) databases (genetic, sequence, functional, phenotypic).
  • Data acquisition from scientific literature and large-scale screening projects.

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Main Results:

  • GXD offers detailed expression patterns in wild-type and mutant mice.
  • Enhanced data content from literature and screening efforts.
  • Improved query and display features for user accessibility.

Conclusions:

  • GXD is a valuable, enhanced resource for researchers studying mouse development and disease.
  • The integration of data provides a holistic view of gene function in biological contexts.
  • GXD supports advanced research through its comprehensive and accessible gene expression information.