Related Experiment Video
Updated: Jul 18, 2026

Synergetic Use of Neural Precursor Cells and Self-assembling Peptides in Experimental Cervical Spinal Cord Injury
Published on: February 23, 2015
Cervical spinal cord neurapraxia in the setting of Klippel-Feil anomaly: a diagnostic and therapeutic challenge
S N Gupta1, J H Piatt, B Belay
1Section of Child Neurology, Department of Pediatrics, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Study Design:
Case report.
Setting:
Temple University Children's Medical Center in USA.
Objectives:
To report a patient whose recurrent and transient episodes of quadriplegia mimicked cervical cord neurapraxia. Cervical spine neuroimaging revealed congenital intersegmental fusion of C5 through C7 (consistent with Klippel-Feil anomaly), corresponding abnormal spinal cord signals on T2-weighted images and enhancing focal lesion opposite the C4 vertebral body. A posterior cervical decompression at C4-C5 and lateral mass fixation was performed, and the episodic quadriplegia has not recurred.
Conclusion:
Understanding of the biomechanics of Klippel-Feil anomaly may facilitate prompt referral for surgical management and avoidance of permanent disability.
Related Concept Videos
Secondary Spinal Cord Injury llI: Pathophysiology
Spinal Cord Injury ll: Pathophysiology
