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[Short-term Lycopersicum esculentum consumption may increase plasma high density lipoproteins and decrease oxidative

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Consuming concentrated tomato juice for seven days significantly boosted lycopene and HDL cholesterol levels in healthy adults. This dietary intervention shows potential for improving antioxidant status and cardiovascular health markers.

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Area of Science:

  • Nutritional Science
  • Biochemistry
  • Human Physiology

Background:

  • Tomatoes are rich in antioxidants like vitamin C, vitamin E, and lycopene, known for their free radical scavenging properties.
  • The impact of tomato consumption on plasma lipoproteins and oxidative stress in humans remains under-researched.

Purpose of the Study:

  • To investigate the in vivo effects of concentrated tomato juice supplementation on oxidative status and plasma lipoproteins in healthy volunteers.
  • To assess short-term changes following a 7-day dietary intervention.

Main Methods:

  • Seventeen healthy volunteers participated in a 7-day supplementation study with pure concentrated tomato juice.
  • Blood samples were analyzed at baseline, end of supplementation, and 8 days post-supplementation for antioxidant levels (lycopene, a-tocopherol, TRAP, catalase, superoxide dismutase) and plasma lipoproteins.

Main Results:

  • Lycopene levels increased significantly by 48% (p < 0.05) early in the supplementation period.
  • High-density lipoprotein (HDL) cholesterol showed a significant increase of 5.6+/-4.3 mg/dL (p < 0.002), improving the cholesterol/HDL ratio.
  • Total antioxidant capacity (TRAP), catalase, and superoxide dismutase levels did not change significantly.

Conclusions:

  • Dietary supplementation with concentrated tomato juice effectively increases plasma lycopene levels.
  • The intervention led to a significant increase in HDL cholesterol, suggesting a positive impact on lipid profiles.
  • No significant short-term changes were observed in overall antioxidant capacity markers (TRAP, catalase, superoxide dismutase).