Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current perspectives in protein array technology.

Larry J Kricka1, S R Master, T O Joos

  • 1Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. kricka@mail.med.upenn.edu

Annals of Clinical Biochemistry
|November 30, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trends in dermatology eponyms.

JAAD international·2022
Same author

A Biopython-based method for comprehensively searching for eponyms in Pubmed.

MethodsX·2021
Same author

Dry Reagent Tests in the 1880s-Dr Pavy's Pellets and Dr Oliver's Papers.

The journal of applied laboratory medicine·2021
Same author

The Editor's Prerogative in Announcing a New Clinical Laboratory Journal.

Clinical chemistry·2021
Same author

Origins and Evolution of Clinical Laboratory Journals.

Clinical chemistry·2021
Same author

Eponyms in clinical chemistry.

Clinica chimica acta; international journal of clinical chemistry·2020
Same journal

Routine laboratory triage for NT-proBNP elevation may reflect cardiorenal frailty as much as heart failure specificity.

Annals of clinical biochemistry·2026
Same journal

From interpretable NT-proBNP prediction to equitable laboratory stewardship.

Annals of clinical biochemistry·2026
Same journal

Serum Sclerostin Levels in Children with Osteogenesis Imperfecta.

Annals of clinical biochemistry·2026
Same journal

Population-Specific HOMA-IR Reference Ranges in Iraq: Defining Insulin Sensitivity in a Middle Eastern Cohort.

Annals of clinical biochemistry·2026
Same journal

Optimizing Laboratory Quality with Sigma Metrics: Application of CLIA 2024 Total Allowable Error Guidelines.

Annals of clinical biochemistry·2026
Same journal

Suspected thermal amplitude of cryoglobulin likely more clinically significant than size detected: A case report.

Annals of clinical biochemistry·2026
See all related articles

This review covers advancements in two-dimensional protein microarrays and nanoarrays since 2000, focusing on their use in clinical diagnostics and quality control measures.

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Clinical Diagnostics

Background:

  • Two-dimensional protein microarrays and nanoarrays have seen significant development post-2000.
  • Their application in clinical diagnostics is a key area of focus.

Purpose of the Study:

  • To review trends in the development of protein microarrays and nanoarrays since 2000.
  • To analyze progress in array manufacture, assay design, and applications.
  • To emphasize challenges in implementing these arrays for clinical diagnostics.

Main Methods:

  • Review of literature and technological advancements in protein microarray and nanoarray development.
  • Analysis of factors affecting assay performance in pre-analytical and analytical phases.
  • Discussion of quality control and assurance requirements for clinical applications.

Related Experiment Videos

Main Results:

  • Progress in array fabrication and assay design has been substantial.
  • Implementation in clinical diagnostics faces challenges related to pre-analytical and analytical variability.
  • Robust quality control and assurance are crucial for routine clinical use.

Conclusions:

  • Protein microarrays and nanoarrays show promise for clinical diagnostics.
  • Addressing pre-analytical and analytical factors is essential for reliable assay performance.
  • Establishing stringent quality control measures is vital for transitioning these technologies to routine clinical practice.