Related Experiment Video
Updated: Jul 18, 2026
Inducing Acute Liver Injury in Rats via Carbon Tetrachloride (CCl4) Exposure Through an Orogastric Tube
Published on: April 28, 2020
Protective effect of Indigofera aspalathoides against CCl4-induced hepatic damage in rats
B Rajkapoor1, B Jayakar, S Kavimani
1Department of Pharmacology, Vinayaka Mission's College of Pharmacy, Yercaud Road, Salem 636 008, Tamilnadu, India. rajkapoorb@yahoo.co.in
Abstract:
The alcoholic extract of stem of Indigofera aspalathoides was evaluated for its antihepatotoxic activity against CCl(4)-induced hepatic damage in rats. The activity was evaluated by using biochemical parameters, such as serum glutamate pyruvate transaminase (SGPT), serum glutamate oxaloacetate transaminase (SGOT), alkaline phosphatase (ALP), total bilirubin and gama glutamate transpeptidase (GGTP). The histopathological changes of liver sample were compared with respective control. The extract showed remarkable hepatoprotective effect.