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Related Experiment Video

Updated: Jul 18, 2026

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
05:17

A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy

Published on: October 27, 2015

Recent progress in capillary ITP.

Petr Gebauer1, Zdena Malá, Petr Bocek

  • 1Institute of Analytical Chemistry, Academy of Sciences of the Czech Republic, Brno, Czech Republic.

Electrophoresis
|December 1, 2006
PubMed
Summary

Capillary Isotachophoresis (ITP) concentrates trace analytes from microliters to picoliters, enhancing analytical separations. This review summarizes advancements in ITP methods, instrumentation, and applications since 2002.

Area of Science:

  • Analytical Chemistry
  • Separation Science

Background:

  • Isotachophoresis (ITP) is a powerful technique for concentrating trace analytes.
  • Its capillary format enables significant volume reduction, from microliters to picoliters.
  • ITP is crucial in multistage and multidimensional separation strategies.

Purpose of the Study:

  • To review and summarize the progress of analytical capillary Isotachophoresis (ITP) since 2002.
  • To consolidate recent advancements in ITP methodology, instrumentation, and applications.
  • To include studies employing ITP principles within complex separation schemes.

Main Methods:

  • Comprehensive literature review of nearly 100 papers published since 2002.
  • Analysis of methodological novelties in ITP.

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Last Updated: Jul 18, 2026

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  • Evaluation of instrumental developments and analytical applications of ITP.
  • Main Results:

    • Significant progress in analytical capillary ITP has been made since 2002.
    • Novel methods, improved instrumentation, and diverse analytical applications have emerged.
    • ITP continues to be integrated into sophisticated multistage and multidimensional separations.

    Conclusions:

    • Analytical capillary ITP has advanced considerably, offering enhanced analyte concentration capabilities.
    • The technique remains a vital component in complex analytical separation schemes.
    • Continued research promises further innovations in ITP technology and applications.