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Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

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Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
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Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
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Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Related Experiment Video

Updated: Jul 18, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
05:35

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

[Resistant anemia in resistant patients].

D Bär1, D I Keller, C von Garnier

  • 1Medizinische Poliklinik, Universitätsspital Basel.

Praxis
|December 2, 2006
PubMed
Summary

A 93-year-old man with severe anemia received 48 palliative blood transfusions due to refusal of diagnostic tests. An ethics committee consultation provided a reasonable treatment solution for this complex geriatric anemia case.

Area of Science:

  • Geriatrics
  • Hematology
  • Medical Ethics

Background:

  • Severe anemia in the elderly presents diagnostic challenges.
  • Patient autonomy significantly impacts treatment decisions in geriatric care.
  • Gastrointestinal bleeding is a common cause of anemia in older adults.

Observation:

  • A 93-year-old male presented with severe anemia, suspected to be gastrointestinal in origin.
  • The patient refused all diagnostic investigations, opting solely for palliative red blood cell transfusions.
  • Over six months, the patient received 48 units of packed red blood cells without further diagnostic or therapeutic interventions.

Findings:

  • The case highlights the ethical dilemma of balancing patient refusal of care with medical necessity in severe anemia.

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Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
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Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

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Last Updated: Jul 18, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
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A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level

Published on: January 19, 2024

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
11:59

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

  • Consultation with a local ethics committee was crucial in navigating this complex clinical scenario.
  • A consensus was reached, leading to a reasonable and ethically sound treatment strategy.

    • Implications:

    • This case underscores the importance of multidisciplinary ethical review in managing challenging geriatric hematology cases.
    • It emphasizes the need for tailored approaches that respect patient autonomy while addressing critical health issues.
    • The findings suggest that ethical frameworks can guide decision-making when standard treatment protocols are hindered by patient preferences.