Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Acute Kidney Injury II: Pathophysiology

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prognostic impact of acute kidney injury on one-year survival in patients undergoing high-risk PCI with Impella support.

Scientific reports·2026

Same author

An association of ABCG8: rs11887534 polymorphism and HDL-cholesterol response to statin treatment in the Polish population.

Pharmacological reports : PR·2021

Same author

The activation of complement system in different types of renal replacement therapy.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society·2020

Same author

Reversal of stage 5 chronic kidney disease by aortic valve replacement in kidney transplant recipient: a case report.

BMC cardiovascular disorders·2020

Same author

Bone Metabolism Parameters in Hemodialysis Patients With Chronic Kidney Disease and in Patients After Kidney Transplantation.

Physiological research·2019

Same author

Trichostatin A Inhibits Rhabdomyosarcoma Proliferation and Induces Differentiation through MyomiR Reactivation.

Folia biologica·2019

Search research articles

Related Experiment Video

Updated: Jul 18, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Circulating adhesion molecules during kidney allograft reperfusion.

L Domański¹, M Gryczman, A Pawlik

¹Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, 70111 Szczecin, al. Powstańców Wlkp 72, Poland. domanle@sci.pam.szczecin.pl

Transplant Immunology

|December 2, 2006

Summary

Early kidney transplant rejection involves increased adhesion molecules like ICAM-1. Elevated ICAM-1 before transplantation predicts acute graft rejection, suggesting its role in the process.

Related Experiment Videos

Last Updated: Jul 18, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection

Mouse Kidney Transplantation: Models of Allograft Rejection

Published on: October 11, 2014

Area of Science:

Transplantation immunology
Vascular biology

Background:

Adhesion molecule expression is critical in early transplant failure.
Understanding these molecules aids in predicting and managing graft outcomes.

Purpose of the Study:

To investigate the release of adhesion molecules during early kidney allograft reperfusion.
To correlate adhesion molecule levels with delayed graft function (DGF) and acute rejection (AR).

Main Methods:

Studied 49 renal transplant recipients, including those with DGF and AR.
Measured plasma concentrations of E-selectin, VCAM-1, and ICAM-1 before reperfusion and 3 minutes after.

Main Results:

Plasma levels of E-selectin, VCAM-1, and ICAM-1 increased significantly after reperfusion.
Elevated ICAM-1 in the iliac vein before reperfusion correlated with AR.
No significant differences in adhesion molecules were found related to DGF.

Conclusions:

Adhesion molecules, particularly ICAM-1, are released early after kidney reperfusion.
Elevated pre-transplant ICAM-1 may indicate a higher risk of acute graft rejection.