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Related Concept Videos

Factors Affecting Drug Distribution: Miscellaneous Factors01:19

Factors Affecting Drug Distribution: Miscellaneous Factors

Drug distribution in the human body is a complex process influenced by various individual factors, including age, pregnancy, obesity, diet, body water composition, pH levels, and specific disease conditions.
Age plays a significant role due to differences in body composition among different age groups. Infants, for instance, have a higher proportion of total body water and lower albumin levels, a protein that binds drugs in the bloodstream. This unique composition in infants enhances the...
Factors Affecting Protein-Drug Binding: Patient-Related Factors01:29

Factors Affecting Protein-Drug Binding: Patient-Related Factors

Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Factors Influencing Drug Absorption: Disease States and Pharmacology01:25

Factors Influencing Drug Absorption: Disease States and Pharmacology

Multiple disease states can significantly influence the oral drug absorption process by affecting blood flow and the functionality of the gastrointestinal (GI) system. Various GI diseases, including conditions that alter GI motility, such as diarrhea, decreased acid secretions (achlorhydria), and infections, have been associated with reduced drug absorption.
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Biopharmaceutical Factors Influencing Drug Product Design: Overview01:22

Biopharmaceutical Factors Influencing Drug Product Design: Overview

Rational drug product design integrates knowledge of the drug’s physicochemical properties, formulation components, manufacturing techniques, and intended route of administration. Each factor influences the drug’s performance, including how it is released, absorbed, and eliminated in the body.The physicochemical properties of a drug—such as solubility, stability, and particle size—affect its compatibility with excipients and the choice of dosage form. Excipients, though pharmacologically...

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Related Experiment Videos

Factors affecting collaborative care between pharmacists and physicians.

William R Doucette1, Justin Nevins, Randal P McDonough

  • 1College of Pharmacy, University of Iowa, S518 PHAR, Iowa City, IA 52242, USA. william-doucette@uiowa.edu

Research in Social & Administrative Pharmacy : RSAP
|December 2, 2006
PubMed
Summary

Pharmacists and physicians can improve patient care through collaboration. Key factors for successful pharmacist-physician collaboration include professional interaction, trustworthiness, and clear role specification.

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Area of Science:

  • Pharmacy Practice
  • Health Services Research
  • Interprofessional Collaboration

Background:

  • Effective medication management is crucial for positive patient outcomes.
  • Pharmacist-physician collaboration is increasingly important for optimizing drug therapy.
  • Factors influencing this collaboration are not well understood.

Purpose of the Study:

  • To identify key factors influencing collaborative care between pharmacists and physicians.
  • To understand these influences from the perspective of pharmacists.

Main Methods:

  • A national survey of 321 innovative pharmacists was conducted.
  • Data collected on individual, contextual, and exchange characteristics.
  • Hierarchical linear regression analysis used to model collaborative care.

Main Results:

  • A 53.4% response rate was achieved (n=166).
  • The model explained 80.5% of the variance in collaborative care (R²=0.805, P<.001).
  • Professional interaction, trustworthiness, and role specification significantly predicted collaborative care.

Conclusions:

  • The collaborative working relationship model effectively explains pharmacist-physician collaboration.
  • Future research should utilize these findings.
  • Pharmacists should focus on building trust and defining clinical roles for successful collaboration.