Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Delayed early proprioceptive information processing in schizophrenia.

Sidse M Arnfred1, Ralf P Hemmingsen, Josef Parnas

  • 1Department of Psychiatry, Hvidovre Hospital,University Hospital of Copenhagen, Brøndbyøstervej 160, 2605 Brøndby, Denmark. s.arnfred@tdcadsl.dk

The British Journal of Psychiatry : the Journal of Mental Science
|December 2, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ipseity-Disturbance and the Nature of Self-Disorder in Schizophrenia: Clarifying Conceptual and Empirical Foundations (a Constructive Reply to Feyaerts and Sass).

Schizophrenia bulletin·2026
Same author

Basic Self-disorders Across Psychiatric Diagnoses and Risk Syndromes: An Updated Meta-analysis.

Schizophrenia bulletin·2026
Same author

The danish version of patient reported outcomes measurement information system depression and anxiety short-forms (PROMIS-D-SF 6a and PROMIS-A-SF 6a) are promising tools to screen for anxiety and depression.

BMC psychiatry·2026
Same author

Long-term diagnostic and social outcomes after first psychiatric hospitalization.

European psychiatry : the journal of the Association of European Psychiatrists·2026
Same author

Emotion regulation as a transdiagnostic treatment construct across group cognitive behavioral therapies for adult anxiety and depression.

Journal of consulting and clinical psychology·2025
Same author

Clinical Activity and Psychopathological Knowledge Are Related to Real-World Performance of Leading International Psychiatrists in Diagnosing Schizophrenia Spectrum Disorders.

Psychopathology·2025
Same journal

The pressurised leaky funnel: rethinking recruitment, selection and retention in the UK psychiatry workforce.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Cutting through stigma: psychiatry and neurosurgery working together.

The British journal of psychiatry : the journal of mental science·2026
Same journal

A fourth pillar for evidence-based medicine: implications for psychiatry - CORRIGENDUM.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Understanding negative perceptions of psychiatrists on social media: lessons from public discourse and professional self-reflection.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Attachment-informed psychopharmacology in psychiatric care.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Acceptability and accuracy of point-of-care monitoring of lithium levels.

The British journal of psychiatry : the journal of mental science·2026
See all related articles

Schizophrenia patients show delayed brain responses in proprioception tasks, suggesting a corollary discharge deficiency rather than a filtering issue. Further research is needed to confirm these findings.

Area of Science:

  • Neuroscience
  • Psychiatry

Background:

  • Disordered proprioception was proposed as a core feature of schizophrenia in 1953.
  • Proprioception, the sense of self-movement and body position, may be impaired in schizophrenia.

Purpose of the Study:

  • To investigate proprioceptive event-related potentials in unmedicated schizophrenia patients.
  • To test the "deficiency of corollary discharge" and "filtering" theories of schizophrenia.

Main Methods:

  • Utilized a novel proprioceptive event-related potential paradigm involving load changes.
  • Studied 12 unmedicated male outpatients with schizophrenia and 24 healthy controls.

Main Results:

  • Schizophrenia patients exhibited delayed early contralateral parietal activity.

Related Experiment Videos

  • Increased amplitude of later central activity was observed in patients.
  • Proprioceptive gating remained unaffected in the patient group.

    • Conclusions:

    • Findings support the "deficiency of corollary discharge" model of schizophrenia.
    • Results do not align with the "filtering" theory of schizophrenia.
    • Further studies with psychiatric controls are required to validate the specificity of these proprioceptive abnormalities.