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Updated: Jul 18, 2026

Improved Registration of 3D CT Angiography with X-ray Fluoroscopy for Image Fusion During Transcatheter Aortic Valve Implantation
Published on: June 3, 2018
Registration of 3D computed tomographic images with interventional systems: implications for catheter ablation of
Jasbir Sra1, Girish Narayan, David Krum
1Electrophysiology Laboratories, Aurora Sinai/St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health--Milwaukee Clinical Campus, Milwaukee, WI, USA. bdanek@hrtcare.com
Insights
Image registration improves catheter ablation for complex arrhythmias like atrial fibrillation (AF). This technique enhances intra-procedure guidance by integrating imaging data, aiming for better therapeutic outcomes and overcoming current limitations.
Area of Science:
- Cardiovascular medicine
- Medical imaging
- Interventional cardiology
Background:
- Catheter ablation shows promise for treating complex arrhythmias, including atrial fibrillation (AF).
- Current limitations include long procedure times, suboptimal outcomes, and inadequate intra-procedure image guidance.
- Fluoroscopy lacks contrast differentiation, and pre-procedural imaging (CT) lacks real-time catheter tracking.
Purpose of the Study:
- To review the evolving concept of image registration for delivering therapy in cardiac arrhythmias.
- To highlight the potential of integrating pre-procedural imaging with real-time data for improved ablation procedures.
Main Methods:
- Review of current literature on image registration techniques in cardiac ablation.
- Discussion of integrating anatomical imaging (e.g., CT) with electrophysiological mapping systems.
- Exploration of methods for real-time catheter tracking and image guidance.
Main Results:
- Image registration offers a pathway to enhance anatomical visualization during catheter ablation.
- Combining pre-procedural imaging with real-time tracking can improve procedural accuracy and efficiency.
- This approach addresses the limitations of traditional fluoroscopy and non-navigating imaging modalities.
Conclusions:
- Image registration is a key evolving concept for improving catheter ablation therapies.
- Integrating diverse imaging modalities and tracking systems can overcome current procedural challenges.
- Enhanced image guidance through registration promises better outcomes for patients with cardiac arrhythmias.
Abstract:
Despite the great promise catheter ablation offers in the treatment of complex arrhythmias such as atrial fibrillation (AF), long procedure times and somewhat suboptimal results hinder the widespread use of this technique. As fluoroscopy does not provide contrast differentiation between the area of interest and the surrounding structures, there is a lack of proper intra procedure image guidance. Segmentation of anatomical structures such as the left atrium (LA) can be performed using images obtained with modalities such as computed tomography (CT). However, unlike the cardiac mapping systems, these imaging systems do not track catheters in real time. This review addresses the evolving concept of image registration to deliver therapy in cardiac arrhythmias.
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An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
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