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Updated: Jul 18, 2026
04:14
Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
Published on: February 28, 2025
[Acute acalculous cholecystitis: pathophysiology and treatment]
Filippo Ferrarese1, Vincenzo Cecere, Gennaro Fabiano
1Dipartimento di Scienze Chirurgiche Generali e Specialistiche, Sezione di Chirurgia Generale, Università degli Studi di Bari.
Annali Italiani Di Chirurgia
|December 5, 2006
Summary
Acute acalculous cholecystitis, often seen in trauma patients, presents diagnostic challenges. Early surgical intervention is crucial for improving outcomes and reducing mortality.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Diagnostic Imaging
Context:
- Acute acalculous cholecystitis (AACC) is a distinct gallbladder condition with unclear diagnostic criteria and multiple risk factors.
- AACC incidence can be high (up to 90%) in critically ill patients, particularly those with severe multiple trauma.
- Delayed diagnosis and treatment significantly increase morbidity and mortality rates.
Purpose:
- To review the diagnostic and management strategies for acute acalculous cholecystitis.
- To evaluate the effectiveness of various imaging modalities in diagnosing AACC.
- To emphasize the importance of timely surgical intervention in AACC cases.
Summary:
- This study reviewed 16 patients operated for AACC, highlighting diagnostic challenges and the role of imaging.
- Ultrasound (US) was the primary diagnostic tool due to speed and accessibility, with CT scans providing further detail when needed.
- Early cholecystectomy within 24 hours was performed, based on evidence linking gallbladder ischemia to disease progression.
Impact:
- Early surgical intervention in AACC can lead to low morbidity rates.
- Despite prompt treatment, the mortality rate for AACC in this study was 18.7%.
- Improved diagnostic accuracy and timely management are essential for reducing AACC-related mortality.
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