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Postoperative OCT Microstructural Changes as Predictors of Visual Prognosis Following Epiretinal Membrane Peeling: A
Weifeng Min1, Yanchun Zhu1, Xinxin Li1
1Department of Fundus Disease, Huzhou Aier Eye Hospital, 313100 Huzhou, Zhejiang, China.
Annali Italiani Di Chirurgia
|July 17, 2026
Summary
Early optical coherence tomography (OCT) measurements of central macular thickness (CMT) after epiretinal membrane surgery can predict visual outcomes. Lower CMT at one month post-surgery indicates a better prognosis for idiopathic macular epiretinal membrane (iERM) patients.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Surgical Outcomes
Background:
- Idiopathic macular epiretinal membrane (iERM) causes retinal distortion, impacting vision and quality of life.
- Vitrectomy with membrane peeling is a standard treatment for iERM.
Purpose of the Study:
- To assess the predictive value of early postoperative optical coherence tomography (OCT) microstructural changes for visual prognosis in iERM patients undergoing vitrectomy.
- To identify early indicators of visual recovery following iERM surgery.
Main Methods:
- Retrospective analysis of 110 iERM patients staged by OCT.
- Patients underwent 23-gauge vitrectomy with membrane peeling.
- Best-corrected visual acuity (BCVA) and OCT parameters (CMT, SFCT, NFCT, TFCT) were measured preoperatively and at 1 and 3 months postoperatively.
Main Results:
- Postoperative OCT parameters and BCVA improved across all stages, with greater improvement in Stage I patients.
- Lower central macular thickness (CMT) at 1 month post-surgery was significantly associated with favorable visual outcomes at 6 months (OR=0.98).
- Stage I patients showed significantly better outcomes compared to Stage II and III.
Conclusions:
- Postoperative recovery in iERM patients is stage-dependent.
- Early postoperative CMT measured by OCT is a valuable indicator for predicting visual prognosis.
- Integrating early OCT assessment into clinical follow-up can aid in individualized patient counseling and prognosis.