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Related Experiment Video

Updated: Jul 18, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Ghost cell odontogenic carcinoma.

S P Nazaretian¹, M E Schenberg, I Simpson

¹Department of Anatomical Pathology, Southern Cross Pathology, Southern Health, Monash Medical Centre, 246 Clayton Road, Clayton, Vic. 3168, Australia. simon.nazaretian@med.monash.edu.au <simon.nazaretian@med.monash.edu.au>

International Journal of Oral and Maxillofacial Surgery

|December 5, 2006

Summary

Ghost cell odontogenic carcinoma (GCOC) is a rare malignant tumor. This case report details a middle-aged male with a maxillary GCOC, highlighting the need for more research on this aggressive odontogenic neoplasm.

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Last Updated: Jul 18, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection

Published on: August 15, 2025

Area of Science:

Oral and Maxillofacial Pathology
Odontogenic Tumors
Neoplasia

Background:

Ghost cell odontogenic carcinoma (GCOC) represents the malignant progression of calcifying cystic odontogenic tumors and dentinogenic ghost cell tumors.
Odontogenic carcinomas are rare malignant neoplasms originating from odontogenic epithelium.

Observation:

A middle-aged male presented with a slowly enlarging maxillary tumor.
The patient was initially asymptomatic, but developed pain preceding the clinical presentation.
Surgical excision revealed a tumor consistent with GCOC.

Findings:

Histopathological diagnosis confirmed ghost cell odontogenic carcinoma.
The tumor exhibited characteristic ghost cells within the neoplastic odontogenic epithelium.

Implications:

This case underscores the clinical presentation and diagnosis of GCOC.
Further case reports are crucial for a comprehensive understanding of GCOC's behavior and treatment.
Increased awareness and reporting are vital for advancing research on this rare malignant odontogenic tumor.