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Related Experiment Video

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The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project

The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project

Published on: November 12, 2009

PATRIC: the VBI PathoSystems Resource Integration Center.

E E Snyder¹, N Kampanya, J Lu

¹Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, USA. eesnyder@vbi.vt.edu

Nucleic Acids Research

|December 5, 2006

Summary

The PathoSystems Resource Integration Center (PATRIC) offers a comprehensive bioinformatics resource for NIAID priority pathogens. This resource integrates genome, proteome, and metabolic data to accelerate the development of drugs, vaccines, and diagnostics.

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Area of Science:

Bioinformatics
Infectious Disease Research
Genomics

Background:

The National Institute of Allergy and Infectious Diseases (NIAID) funds eight Bioinformatics Resource Centers (BRCs).
PATRIC is one such BRC, focusing on NIAID priority pathogens.

Purpose of the Study:

To establish a centralized data and analysis resource for specific NIAID priority pathogens.
To facilitate research and development of countermeasures, including drugs, vaccines, and diagnostics.

Main Methods:

Implementing a three-pronged curation strategy: 'breadth first', 'targeted', and 'integrative'.
Utilizing standardized protocols for whole-genome and proteome curation.
Leveraging high-throughput experimental data and literature for data integration.

Main Results:

Warehousing complete genome sequences for 17 bacterial and 332 viral species.
Developing a relational database, analytical pipelines, and a user-friendly website.
Providing capabilities for data browsing, querying, visualization, and download.

Conclusions:

PATRIC serves as a vital, growing resource for NIAID priority pathogen research.
The integrated data and analysis tools aim to accelerate countermeasure development.
The platform supports diverse research needs through comprehensive data and functionality.