Related Experiment Video
Updated: Jul 18, 2026

Chemical Reversion of Conventional Human Pluripotent Stem Cells to a Naïve-like State with Improved Multilineage Differentiation Potency
Published on: June 10, 2018
Is the search for alternative sources of human pluripotent stem cells a mistake?
1Research Ethics Program, University of California, San Diego, La Jolla, CA 92103-0612, USA. mdevereaux@ucsd.edu
Abstract:
One response to the controversy in the United States over the moral status of the early embryo has been the proposal that scientists search for alternative sources of pluripotent stem cells. Is this a good idea? The present article argues that it is not. Following a brief look at the ethical standing of the four proposals assessed by the President's Council on Bioethics in 2005, the author addresses the fundamental question of the wisdom of pursuing alternatives to current methods of stem cell derivation. The author concludes that, given the poor prospects for finding alternatives that are both scientifically and ethically sound, and the costs of diverting energy and resources from established embryonic methods, further investment in the search for alternative methods is unwise.
Related Concept Videos
Induced Pluripotent Stem Cells
Somatic cells are...
Induced Pluripotent Stem Cells
Induced Pluripotent Stem Cells
Stem Cell Culture
Embryonic Stem Cells
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Embryonic Stem Cells

