Related Experiment Video
Updated: Jul 18, 2026
Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Relation between plasma oxLDL antibodies and oxLDL in the circulation
Yan Wang1, Xueqiang Fang, Shumei Wang
1Department of Epidemiology and Biostatistics, School of Public Health, Shandong University, no.44 Wen Hua Xi Road, Jinan, Shandong 250012, People's Republic of China.
Objectives:
To investigate the possible relationship between circulating oxLDL and oxLDL Ab concentrations in order to better understand the role of oxLDL Ab in atherosclerosis.
Design:
In a cross-sectional study of 86 patients undergoing ultrasonographic scanning of the carotid artery, concentration of circulating oxLDL and oxLDL Ab were determined by ELISA. For multivariate analysis, we also measured many conventional cardiovascular risk factors. Spearman's rank correlation test and chi-square test were used to evaluate the correlation between circulating oxLDL and oxLDL Ab. A stepwise multiple regression analysis and Logistic regression analysis were used to study the influencing factors.
Results:
There was no linear correlation between circulating oxLDL and oxLDL Ab. Circulating oxLDL was influenced by HDL, systolic blood pressure and body mass index, while only TC was independent factor associating with oxLDL Ab.
Conclusions:
The present study showed that oxLDL was present at a low concentration in the circulation, and that plasma oxLDL had no linear correlation with oxLDL antibodies. However, the issue still needs further study.
Related Concept Videos
01:12The ABO Blood Group
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
01:29Drug Distribution: Plasma Protein Binding
01:24Pulse Oximetry
Purpose
Average SpO2 values are greater than 95%. If the readings fall below 90%, it indicates that...
02:45Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
01:27Oxygen Transport in the Blood
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...