Related Experiment Video
Updated: Jul 18, 2026
Ultrasonographic Evaluation of Salivary Glands for Sjogren's Syndrome: Diagnostic and Monitoring Insights
Published on: October 13, 2023
[Electrophoretic analysis of lacrimal proteins--a diagnostic method in secondary Sjogren syndrome]
Viorica Madalina Cojocaru1, Coziana Ciurtin, Elena Puchianu
1Spitalul Clinic Dr. I. Cantacuzino, Bucuresti.
Purpose:
We analysed and compared electrophoretic tear proteins patterns of healthy subjects and patients with different autoimmune diseases associated with secondary Sjogren's syndrome.
Materials And Methods:
Tears were collected using the Schirmer's method. Proteins were separated by sodium-dodecyl sulfate polyacrylamide gel electrophoresis. The lanes were stained by Coomassie blue and/or silver.
Results:
Lactoferrin, albumin, lipocalin and lysozyme were found to be the main components being identified using molecular weight markers.
Conclusions:
Electrophoretic analysis of tear proteins patterns is a fast, reproducible and simple method which provides information about the possibility of lacrimal gland involvement in auto-immune diseases.
