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Updated: Jul 18, 2026

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Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
Published on: January 22, 2018
[Choroidal hemangioma and epiretinal membrane]
Summary
This study highlights a rare case of choroidal hemangioma with an atypical fluorescein angiography pattern, initially missed by ocular echography. The condition, associated with an epiretinal membrane, caused visual acuity impairment due to cystoid macular edema.
Area of Science:
- Ophthalmology
- Medical Imaging
- Pathology
Background:
- Choroidal hemangiomas are congenital benign vascular tumors, often diagnosed late in life.
- Association with epiretinal membranes is uncommon.
- Diagnostic challenges arise from atypical presentations and imaging limitations.
Observation:
- A patient presented with a choroidal hemangioma exhibiting an unusual fluorescein angiography pattern.
- Ocular echography failed to detect the hemangioma, complicating diagnosis.
- An epiretinal membrane was clinically and angiographically evident.
Findings:
- The choroidal hemangioma demonstrated an atypical fluorescein angiography appearance.
- Diagnostic difficulties were encountered due to negative ocular echography findings.
- Cystoid macular edema was present, significantly impacting visual acuity.
Implications:
- This case underscores the importance of considering rare presentations of choroidal hemangiomas.
- Advanced imaging may be crucial for diagnosing challenging cases.
- Understanding the complex pathogenesis of associated cystoid macular edema is vital for effective management.
