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[Medical treatment of heart failure with preserved left ventricular ejection fraction]

Manuel Anguita Sánchez1, Soledad Ojeda Pineda

  • 1Servicio de Cardiología, Hospital Universitario Reina Sofía, Córdoba, Spain. manuelp.anguita.sspa@juntadeandalucia.es

Revista Espanola De Cardiologia
|December 6, 2006
PubMed

Insights

Diastolic heart failure, also known as heart failure with preserved ejection fraction, has a poor prognosis. Current treatment focuses on managing underlying causes and symptoms, with combination therapy showing promise.

Area of Science:

  • Cardiology
  • Internal Medicine

Context:

  • Diastolic heart failure (DHF) comprises 30%-50% of all heart failure cases.
  • DHF carries a prognosis comparable to systolic heart failure.
  • Current diagnosis relies on clinical criteria and preserved left ventricular ejection fraction (>40%-50%).

Purpose:

  • To review the current understanding and therapeutic approaches for diastolic heart failure.
  • To highlight the diagnostic criteria and prognostic implications of DHF.
  • To discuss evidence-based treatment strategies for managing DHF.

Summary:

  • Diagnosis of DHF requires meeting strict clinical criteria for heart failure with preserved ejection fraction.
  • Therapeutic strategies for DHF are primarily based on treating causal conditions like hypertension and coronary heart disease, controlling heart rate, and managing congestion.
  • Combination therapy involving low-dose diuretics, bradycardiac antihypertensives (beta-blockers, calcium antagonists), and angiotensin antagonists is considered the optimal approach.

Impact:

  • This review provides a concise overview of DHF diagnosis and management.
  • It emphasizes the need for effective therapeutic strategies for DHF, a common and serious condition.
  • The findings support current clinical practice and suggest areas for future research in DHF treatment.

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