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Updated: Jul 18, 2026

Natural Transformation, Protein Expression, and Cryoconservation of the Filamentous Cyanobacterium Phormidium lacuna
Published on: February 1, 2022
Microbial transformation of dehydrocostuslactone by Mucor polymorphosporus
1The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Abstract:
Biotransformation of dehydrocostuslactone (1) by Mucor polymorphosporus yielded four compounds, and their structures were identified as 11alpha,13-dihydrodehydrocostuslactone (2), 3alpha-hydroxy-11alpha,13-dihydrodehydrocostuslactone (3), 3beta-hydroxy-4beta,15,11alpha,13-tetrahydrodehydrocostuslactone (4) and 2beta-hydroxyl-11alpha,13-dihydrodehydrocostuslactone (5), respectively, on the basis of their spectral data. Among them, compound 5 is a new compound.
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