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Lectins: carbohydrate-specific reagents and biological recognition molecules

Nathan Sharon1

  • 1Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel. nathan.sharon@weizmann.ac.il

The Journal of Biological Chemistry
|December 6, 2006
PubMed
Summary

No abstract available in PubMed .

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Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain, which...
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