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Published on: October 30, 2013
A case of T2 muscle-invasive bladder cancer treated with neoadjuvant chemotherapy
Scott M Gilbert1, Cheryl T Lee
1Department of Urology, University of Michigan, 7303 CCGC, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0946, USA.
Background:
A 61-year-old woman with a substantial history of smoking presented with gross hematuria. Cystoscopic evaluation revealed a large bladder tumor.
Investigations:
Cystoscopic evaluation, histological examination, crosssectional imaging.
Diagnosis:
High-grade muscle-invasive transitional cell carcinoma (clinical stage T2N0M0, later confirmed as pathologic stage T3aN0M0).
Management:
Transurethral resection of the bladder tumor, clinical trialbased neoadjuvant treatment with paclitaxel, carboplatin and gemcitabine, and radical cystectomy.