Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ergot and its alkaloids.

Paul L Schiff1

  • 1Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA. pschiff@pitt.edu

American Journal of Pharmaceutical Education
|December 7, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Homodecoupled 1,1- and 1,n-ADEQUATE: Pivotal NMR Experiments for the Structure Revision of Cryptospirolepine.

Angewandte Chemie (International ed. in English)·2015
Same author

The development of USP botanical dietary supplement monographs, 1995-2005.

Journal of natural products·2006
Same author

Alkaloids of Thalictrum angustifolium.

Journal of herbal pharmacotherapy·2004
Same author

In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei.

Phytotherapy research : PTR·2002
Same journal

Behind the Skills Lab: A Qualitative Study of Skills Lab Faculty Workload.

American journal of pharmaceutical education·2026
Same journal

Response to "Using the ACCP Toolkit to evolve the PharmD curriculum".

American journal of pharmaceutical education·2026
Same journal

Response to Johnson & Smith, Jozefczyk, and Posen et al. Regarding "Stop Pressuring Pharmacy Residents to be Licensed by July 1".

American journal of pharmaceutical education·2026
Same journal

Influence of Board-Certified Preceptors on Pharmacy Students' Intention to Pursue Specialty Certification.

American journal of pharmaceutical education·2026
Same journal

FLEXIBLE WORK ARRANGEMENTS IN PHARMACY ACADEMIA - AN OVERDUE IMPERATIVE.

American journal of pharmaceutical education·2026
Same journal

Vocational Health Students Shaping Interprofessional Practice: A Mixed-Methods Study in Community-Based Education.

American journal of pharmaceutical education·2026
See all related articles

This review covers ergot alkaloids, their derivatives, and their therapeutic uses in conditions like migraine and Parkinson's disease. It also briefly touches upon the hallucinogenic properties of lysergic acid diethylamide.

Area of Science:

  • Pharmacology
  • Medicinal Chemistry
  • Ethnobotany

Background:

  • Ergot, a fungus, has a long history of use and toxicity.
  • Ergot alkaloids are a class of compounds with significant pharmacological effects.
  • Understanding ergot's history and chemistry is crucial for its therapeutic applications.

Purpose of the Study:

  • To provide a comprehensive review of ergot and its major alkaloids.
  • To detail the isolation, preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of ergot alkaloids.
  • To briefly discuss the hallucinogenic properties of lysergic acid diethylamide.

Main Methods:

  • Literature review of historical and scientific data on ergot.
  • Analysis of chemical structures and properties of ergot alkaloids.

Related Experiment Videos

  • Pharmacological and therapeutic evaluation of ergot alkaloids and derivatives.

    • Main Results:

    • Detailed description of the history and pharmacognosy of ergot.
    • Elucidation of the isolation, preparation, and chemistry of key ergot alkaloids.
    • Summary of the pharmacodynamics and pharmacotherapeutics of ergot alkaloids for conditions including vascular migraine headaches and Parkinson's disease.
    • Brief overview of lysergic acid diethylamide's hallucinogenic effects.

    Conclusions:

    • Ergot alkaloids possess diverse and significant therapeutic applications.
    • Further research into ergot alkaloid derivatives may yield novel treatments.
    • Educational review provides a foundation for understanding ergot's role in medicine and its derivatives.