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Updated: Jul 18, 2026
06:44
Isolation of Brain-infiltrating Leukocytes
Published on: June 13, 2011
Fungal brain abscesses in leukemia
Fani Athanassiadou1, Athanassios Tragiannidis, Theodotis Papageorgiou
12nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece. atragian@hotmail.com
Indian Pediatrics
|December 8, 2006
Summary
Fungal brain abscesses are a serious risk for children with acute lymphoblastic leukemia (ALL) undergoing chemotherapy. Early diagnosis and treatment are crucial for managing these life-threatening invasive fungal infections.
Area of Science:
- Pediatric Oncology
- Infectious Diseases
- Neuroimaging
Background:
- Invasive fungal infections (IFIs) pose a significant threat to immunocompromised children, particularly those with hematological malignancies.
- The central nervous system is a potential site for disseminated fungal infections originating from extracranial sources.
Observation:
- This report details the diagnostic, radiological, and therapeutic management of two pediatric patients with acute lymphoblastic leukemia (ALL).
- Both patients developed fungal brain abscesses while undergoing chemotherapy.
Findings:
- The study highlights the clinical presentation and imaging characteristics of fungal brain abscesses in this vulnerable pediatric population.
- It underscores the importance of prompt recognition and intervention for successful outcomes.
Implications:
- This case series contributes to understanding the complexities of managing invasive fungal infections in pediatric leukemia.
- It emphasizes the need for a multidisciplinary approach involving oncologists, infectious disease specialists, and radiologists.
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