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Related Experiment Videos

Percutaneous mitral valve repair.

A Marc Gillinov1, John R Liddicoat

  • 1Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic, Cleveland, OH 44195, USA. gillinom@ccf.org

Seminars in Thoracic and Cardiovascular Surgery
|December 13, 2006
PubMed
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Percutaneous mitral valve repair techniques, including annuloplasty and edge-to-edge repair, are emerging as less invasive alternatives to surgery. This report reviews their development, clinical results, and future directions for mitral regurgitation treatment.

Area of Science:

  • Cardiovascular Surgery
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Surgical mitral valve repair is the gold standard for treating mitral regurgitation.
  • Current surgical techniques often involve multiple repair strategies for leaflets and subvalvular apparatus.
  • The need for less invasive treatment options drives innovation in mitral valve repair.

Purpose of the Study:

  • To discuss the surgical basis for percutaneous mitral valve repair approaches.
  • To review the design and outcomes of devices for percutaneous annuloplasty and edge-to-edge repair.
  • To address future challenges in patient selection and clinical trial design for percutaneous mitral valve repair.

Main Methods:

  • Review of preclinical studies and early human clinical experiences with percutaneous mitral valve repair techniques.

Related Experiment Videos

  • Analysis of device designs for percutaneous annuloplasty and edge-to-edge repair.
  • Discussion of existing literature and expert opinion on future directions.

    • Main Results:

    • Novel technologies show significant progress in enabling percutaneous annuloplasty and edge-to-edge mitral valve repair.
    • Early clinical data suggest feasibility and potential efficacy of percutaneous approaches.
    • Surgical foundations are being translated into viable percutaneous strategies.

    Conclusions:

    • Percutaneous mitral valve repair is a rapidly advancing field with the potential to offer less invasive treatment options.
    • Further research and well-designed clinical trials are crucial for optimizing patient selection and validating efficacy.
    • Continued innovation in device technology and procedural techniques is expected.