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Updated: Jul 18, 2026

10:49
Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Antibiotics--an investment worth making?
1Morgenthaler Ventures, 4430 Arapahoe Avenue, Suite 220, Boulder, Colorado 80303, USA. rchris@morgenthaler.com
Nature Biotechnology
|December 13, 2006
Summary
The global antibiotics market is substantial, yet significant risks deter investment in developing novel antibiotic classes. Addressing these risks is crucial for future antimicrobial development.
Area of Science:
- Pharmaceutical Sciences
- Infectious Diseases
- Drug Discovery
Background:
- The global antibiotics market represents a significant economic sector.
- There is a critical and growing need for new classes of antibiotics to combat resistant infections.
- Investor confidence in antibiotic development is currently low due to inherent risks.
Purpose of the Study:
- To analyze the current landscape of the antibiotics market.
- To identify the key risks associated with antibiotic development that deter investment.
- To explore potential strategies for mitigating these risks and encouraging investment in novel antibiotic classes.
Main Methods:
- Market analysis of the global antibiotics sector.
- Risk assessment of drug development pipelines for new antibiotic classes.
- Review of investment trends and barriers in antimicrobial research and development.
Main Results:
- The antibiotics market is economically vast, highlighting its importance.
- The urgent requirement for novel antimicrobial agents is well-established.
- Perceived risks in antibiotic research and development significantly impede investor engagement.
Conclusions:
- Despite the immense market potential and critical need, investment in new antibiotic classes is hampered by substantial risks.
- Overcoming these financial and developmental hurdles is essential for securing the future of antibiotic innovation.
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