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Murine Full-thickness Skin Transplantation
Published on: January 2, 2017
New trends in immunosuppression and immunotherapy
Shuiping Jiang1, Giovanna Lombardi
1Immunoregulation, Department of Nephrology and Transplantation, King's College London, Guy's Hospital, London SE1 9RT, United Kingdom.
International Immunopharmacology
|December 13, 2006
Summary
Regulatory T cells (Tregs) research has advanced significantly, revealing diverse populations and mechanisms. This progress offers new avenues for treating autoimmune diseases and improving transplant tolerance.
Area of Science:
- Immunology
- Translational Medicine
- Immunotherapy
Background:
- Recent research highlights the re-emergence and significance of T suppressor cells, now known as regulatory T cells (Tregs).
- Understanding the diverse populations, generation, and suppression mechanisms of Tregs is a rapidly advancing area in immune regulation.
Discussion:
- The study of Tregs presents new opportunities for immune intervention strategies.
- Advances in understanding Tregs can lead to novel treatments for autoimmune diseases.
- Treg research is crucial for achieving clinical transplantation tolerance.
Key Insights:
- Different populations of regulatory T cells (Tregs) have been identified within the immune system.
- The cellular and molecular targets of Tregs are actively being investigated.
- Unraveling Treg function is key to developing new therapeutic approaches.
Outlook:
- Continued research into Tregs promises breakthroughs in autoimmune disease treatment.
- The field anticipates significant progress in achieving clinical transplantation tolerance through Treg modulation.
- The 7th International Conference on New Trends in Immunosuppression and Immunotherapy showcased these burgeoning translational medicine advances.
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