Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What Are Outliers?01:12

What Are Outliers?

Outliers are observed data points that are far from the least squares line. They have unusual values and need to be examined carefully. Though an outlier may result from erroneous data, at other times, it may hold valuable information about the population under study and should be included in the data. Hence, it is crucial to examine what causes a data point to be an outlier.
The z score is used to find outliers or unusual values. It should be noted that any values beyond -2 and +2 are...
Keystone Species01:39

Keystone Species

Measures of species biodiversity, such as richness (i.e., the number of species present) and evenness (i.e., their relative abundance), describe an ecological community’s structure. Many factors affect community structure, including abiotic factors (e.g., sunlight and nutrients), disturbances (e.g., fire or flood), species interactions (e.g., predation or competition), and chance events (e.g., foreign species invasion). Certain species—such as keystone species—also play a pivotal role in the...
Otto and Diesel Cycle01:27

Otto and Diesel Cycle

An Otto engine is a four-stroke engine that uses a mixture of gasoline and air as the working fuel. The fuel is injected into the cylinder, and the piston is moved completely down so that the cylinder is at maximum volume. By moving the piston up, adiabatic compression takes place. The spark plug ignites the gasoline-air mixture, and the burning fuel adds heat to the system at a constant volume. The heated mixture expands adiabatically and gets further cooled by exhausting heat, and this cyclic...
Osmosis00:47

Osmosis

Approximately 60% to 95% of the weight of living organisms is attributed to water. Therefore, maintaining appropriate water balance within cells is of paramount importance. Osmosis is the movement of water across a semipermeable membrane, such as a cell’s plasma membrane. In living organisms, water plays a crucial role as a solvent—a molecule that dissolves other molecules.Diffusion Versus OsmosisBoth diffusion and osmosis are types of passive transport—cellular transport that does not require...
Osmosis01:30

Osmosis

Osmosis is the movement of free water molecules through a semipermeable membrane.  The water's concentration gradient across the membrane is inversely proportional to the solutes' concentration. Whereas diffusion transports material across membranes and within cells, osmosis transports only water across a membrane, and the membrane limits the diffusion of solutes in the water. Osmosis is a special case of diffusion.
Water, like other substances, moves from a high concentration of free water...
Unusual Results01:16

Unusual Results

Unusual results are those that have a very low chance of occurring. Unusual results can be identified using probabilities and the range rule of thumb. In problems involving probability, unusual results can be observed in 2 instances – an unusually high number of successes or an unusually low number of successes.
According to the range rule of thumb, any value above or below two standard deviations, 2σ  from the mean, μ  is considered unusual.
Maximum unusual value = μ + 2σ
Minimum unusual value...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and validation of blood-based diagnostic biomarkers for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) using EpiSwitch<sup>®</sup> 3-dimensional genomic regulatory immuno-genetic profiling.

Journal of translational medicine·2025
Same author

Clinical Utility of the EpiSwitch CiRT Test to Guide Immunotherapy Across Solid Tumors: Interim Results from the PROWES Study.

Cancers·2025
Same author

Blood-Epigenetic Biomarker Associations with Tumor Immunophenotype in Patients with Urothelial Carcinoma from JAVELIN Bladder 100.

Cancers·2025
Same author

Paradigm Lost.

Cancers·2025
Same author

EpiSwitch PSE Blood Test Reduces Unnecessary Prostate Biopsies: A Real-World Clinical Utility Study.

Cancers·2025
Same author

A New Blood-Based Epigenetic Diagnostic Biomarker Test (EpiSwitch<sup>®®</sup> NST) with High Sensitivity and Positive Predictive Value for Colorectal Cancer and Precancerous Polyps.

Cancers·2025

Related Experiment Video

Updated: Jul 18, 2026

Operant Sensation Seeking in the Mouse
08:39

Operant Sensation Seeking in the Mouse

Published on: November 10, 2010

What is so special about oskar wild?

William O'Gorman1, Alexandre Akoulitchev

  • 1Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

Science'S STKE : Signal Transduction Knowledge Environment
|December 14, 2006
PubMed
Summary

A mutation in the Drosophila Oskar gene reveals a new function for the 3' untranslated region (UTR) of its mRNA in development. This highlights the crucial regulatory roles of noncoding genomic elements in multicellular organisms.

Area of Science:

  • Developmental Biology
  • Genomics
  • Molecular Biology

Background:

  • Regulatory noncoding RNAs are crucial in various biological fields.
  • Noncoding genomic elements are increasingly recognized for their regulatory roles.

Purpose of the Study:

  • To investigate the function of the 3' untranslated region (UTR) of the Drosophila Oskar mRNA.
  • To explore the role of noncoding genomic elements in development.

Main Methods:

  • Genetic mutation analysis in Drosophila.
  • mRNA analysis.

Main Results:

  • A mutation in the Drosophila Oskar gene identified a novel developmental function for its 3' UTR.
  • The 3' UTR of oscar mRNA plays a role in regulating gene expression during development.

More Related Videos

Rapid Deletion Production in Fungi via Agrobacterium Mediated Transformation of OSCAR Deletion Constructs
11:24

Rapid Deletion Production in Fungi via Agrobacterium Mediated Transformation of OSCAR Deletion Constructs

Published on: June 12, 2017

PyOKR: A Semi-Automated Method for Quantifying Optokinetic Reflex Tracking Ability
05:26

PyOKR: A Semi-Automated Method for Quantifying Optokinetic Reflex Tracking Ability

Published on: April 12, 2024

Related Experiment Videos

Last Updated: Jul 18, 2026

Operant Sensation Seeking in the Mouse
08:39

Operant Sensation Seeking in the Mouse

Published on: November 10, 2010

Rapid Deletion Production in Fungi via Agrobacterium Mediated Transformation of OSCAR Deletion Constructs
11:24

Rapid Deletion Production in Fungi via Agrobacterium Mediated Transformation of OSCAR Deletion Constructs

Published on: June 12, 2017

PyOKR: A Semi-Automated Method for Quantifying Optokinetic Reflex Tracking Ability
05:26

PyOKR: A Semi-Automated Method for Quantifying Optokinetic Reflex Tracking Ability

Published on: April 12, 2024

Conclusions:

  • The noncoding regions of the genome, when transcribed, possess essential regulatory functions.
  • These functions are fundamental for coordinated gene expression and the development of multicellular organisms.