[Developments of liquid-phase microextraction based on hollow fiber].

Area of Science:

• Analytical Chemistry
• Separation Science

Context:

• Sample preparation is crucial for accurate analytical results.
• Traditional methods can be time-consuming, costly, and generate significant waste.
• There is a need for efficient, green, and integrated sample preparation techniques.

Purpose:

• To review the principles, setup, and applications of hollow fiber-based liquid-phase microextraction (HF-LPME).
• To highlight HF-LPME as an environmentally benign and efficient sample preparation technique.
• To discuss its integration with chromatographic and electrophoretic separation methods.

Summary:

• Hollow fiber-based liquid-phase microextraction (HF-LPME) integrates sampling, extraction, and concentration into a single, environmentally friendly step.
• This technique is simple, low-cost, and virtually solvent-free, offering excellent sample clean-up and high extraction recovery.
• HF-LPME is versatile and can be readily coupled with high-performance liquid chromatography (HPLC), gas chromatography (GC), and capillary electrophoresis (CE).

Impact:

• Provides a greener alternative to conventional sample preparation methods.
• Enhances analytical efficiency through improved recovery and reduced analysis time.
• Facilitates wider adoption of microextraction techniques in various analytical laboratories.