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Updated: Jul 18, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Clinical evaluation in predicting childhood obstructive sleep apnea.
Zhifei Xu1, Daniel Ka Leung Cheuk, So Lun Lee
1Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Clinical examination and lateral neck X-rays can help detect obstructive sleep apnea (OSA) in children. Combining these findings with symptoms like mouth breathing improves diagnostic accuracy for pediatric OSA.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Diagnostic Imaging
Background:
- Obstructive sleep apnea (OSA) is a common condition in children.
- Accurate diagnosis of pediatric OSA is crucial for timely intervention.
- Current diagnostic methods may have limitations in accessibility and invasiveness.
Purpose of the Study:
- To evaluate the utility of clinical observation, physical examination, and lateral neck radiography in identifying clinically significant OSA in children.
- To compare the effectiveness of these methods against polysomnography (PSG) findings.
Main Methods:
- Retrospective review of 50 children (4-18 years) referred for suspected OSA.
- Clinical assessments included history, physical exam, and lateral neck X-ray for postnasal space.
- Overnight PSG was performed to define OSA (apnea-hypopnea index [AHI] > 5) versus primary snoring (AHI ≤ 5).
Main Results:
- Thirty-one children had significant OSA; 19 were primary snorers.
- Risk factors like allergic rhinitis and obesity were similar between groups.
- Predictors for OSA included observable apnea, enuresis, naps, mouth breathing, enlarged tonsils, and adenoid hypertrophy on X-ray.
- Combined predictors achieved high sensitivity (90.3% to 93.5%) for OSA detection.
Conclusions:
- Clinical examination and lateral upper airway radiography show promise in screening for pediatric OSA.
- Combining these findings may aid in identifying children requiring further investigation and intervention for OSA.
- This approach could facilitate earlier diagnosis and management of OSA in pediatric populations.
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