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Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Clinical evaluation in predicting childhood obstructive sleep apnea
Zhifei Xu1, Daniel Ka Leung Cheuk, So Lun Lee
1Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, People's Republic of China.
Insights
Clinical examination and lateral neck X-rays can help detect obstructive sleep apnea (OSA) in children. Combining these findings with symptoms like mouth breathing improves diagnostic accuracy for pediatric OSA.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Diagnostic Imaging
Background:
- Obstructive sleep apnea (OSA) is a common condition in children.
- Accurate diagnosis of pediatric OSA is crucial for timely intervention.
- Current diagnostic methods may have limitations in accessibility and invasiveness.
Purpose of the Study:
- To evaluate the utility of clinical observation, physical examination, and lateral neck radiography in identifying clinically significant OSA in children.
- To compare the effectiveness of these methods against polysomnography (PSG) findings.
Main Methods:
- Retrospective review of 50 children (4-18 years) referred for suspected OSA.
- Clinical assessments included history, physical exam, and lateral neck X-ray for postnasal space.
- Overnight PSG was performed to define OSA (apnea-hypopnea index [AHI] > 5) versus primary snoring (AHI ≤ 5).
Main Results:
- Thirty-one children had significant OSA; 19 were primary snorers.
- Risk factors like allergic rhinitis and obesity were similar between groups.
- Predictors for OSA included observable apnea, enuresis, naps, mouth breathing, enlarged tonsils, and adenoid hypertrophy on X-ray.
- Combined predictors achieved high sensitivity (90.3% to 93.5%) for OSA detection.
Conclusions:
- Clinical examination and lateral upper airway radiography show promise in screening for pediatric OSA.
- Combining these findings may aid in identifying children requiring further investigation and intervention for OSA.
- This approach could facilitate earlier diagnosis and management of OSA in pediatric populations.
Objective:
To determine whether parents' observation, clinical examination, and lateral upper airway radiograph are useful in detecting clinically significant obstructive sleep apnea (OSA) in children.
Method:
We retrospectively reviewed data of 50 children aged 4 to 18 years who were consecutively referred to a sleep clinic for suspected OSA. All subjects underwent clinical assessments including standardized history collection, physical examination, and lateral neck radiograph for measurement of postnasal space. Each child underwent overnight polysomnography on the night of clinical assessments. Patients with clinically significant OSA, defined as apnea-hypopnea index (AHI) > 5, were compared with primary snorers, defined as AHI < or = 5.
Results:
Thirty-one children had clinically significant OSA, and 19 children were primary snorers. The prevalence of risk factors including allergic rhinitis, obesity, and craniofacial anomaly was similar between the two groups. Observable apnea during sleep, nocturnal enuresis, intrusive naps, mouth breathing, enlarged tonsils, and radiologic features of upper airway narrowing due to adenoid hypertrophy were found to be predictors for clinically significant OSA. Combining upper airway narrowing and mouth breathing or nocturnal enuresis had a sensitivity of 90.3%, and combining all six predictors had a sensitivity of 93.5% of detecting OSA.
Conclusion:
Combining clinical and radiologic findings might be helpful to screen for children with clinically significant OSA who need earlier investigation and intervention.
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