Related Experiment Video
Updated: Jul 18, 2026

In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
Published on: June 6, 2025
Combined effects of carbon dioxide laser and fluoride on demineralized primary enamel: an in vitro study
E P S Tagliaferro1, L K A Rodrigues, M Nobre Dos Santos
1Faculty of Dentistry of Piracicaba, State University of Campinas, Piracicaba, Brazil.
Abstract:
This in vitro study aimed at evaluating the efficacy of a CO(2) laser (10.6 microm) alone or combined with acidulated phosphate fluoride (APF) on the inhibition of lesion progression in primary enamel. The specimens were treated with/without CO(2) laser and/or APF and submitted to pH cycling. Microhardness analysis was performed and the enamel mineral loss values were obtained. The groups treated with laser and/or APF presented lower mineral loss when compared to the control group (p < 0.05). Laser irradiation alone or combined with APF decreased lesion progression in primary enamel. However, the combined treatment did not show any significant additional effect.

